Montair vs. Alternatives Decision Guide
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Montair (Montelukast): Best for mild-moderate asthma with seasonal allergies. Once-daily oral tablet, low cost, minimal side effects.
Inhaled Corticosteroids: First-line for persistent asthma. Reduce inflammation but require inhaler technique.
Antihistamines: Effective for allergy symptoms but limited asthma benefit.
Biologics: Reserved for severe asthma not controlled by standard treatments. High cost, injectable administration.
If you’ve been prescribed Montair for asthma or allergic rhinitis, you’ve probably wondered: is this the best option or are there cheaper, safer, or more effective drugs out there? This guide breaks down Montair (montelukast) side by side with the most common alternatives, so you can weigh the pros and cons based on how the drug works, typical side effects, cost, and who benefits most.
What is Montair (montelukast)?
Montair is a brand name for montelukast, a leukotriene receptor antagonist (LTRA) taken orally to prevent asthma attacks and relieve seasonal allergy symptoms. It comes in tablets, chewable tablets, and granules, usually once a day. The drug blocks leukotrienes - inflammatory chemicals released after exposure to allergens or irritants - which helps keep airways open and reduces mucus production.
How Montair fits into the LTRA class
Leukotriene receptor antagonists are oral medications that target the leukotriene pathway, a key driver of bronchoconstriction and nasal inflammation. By binding to the cysteinyl‑leukotriene receptor CysLT1, they prevent leukotrienes from tightening airway muscles. Montair is one of the most widely prescribed LTRAs because of its once‑daily dosing and broad approval for both asthma and allergic rhinitis.
Common alternatives to Montair
When doctors consider alternatives, they look at other drug classes or different brands within the same class:
- Singulair is another brand of montelukast, identical in chemical composition but sometimes priced differently depending on the pharmacy.
- Zafirlukast is an older LTRA that requires twice‑daily dosing and has a higher risk of liver enzyme elevation.
- Inhaled corticosteroids (ICS) such as fluticasone or budesonide, are the cornerstone of long‑term asthma control, reducing airway inflammation at the source.
- Antihistamines like cetirizine or loratadine work by blocking histamine receptors, helping with sneezing and itchy eyes but offering limited asthma benefit.
- Biologic therapies such as omalizumab target IgE or specific cytokines, reserved for severe asthma that doesn’t respond to standard inhalers.
Decision criteria - when to choose Montair or an alternative
Ask yourself these questions before settling on a drug:
- Severity of asthma: Mild‑to‑moderate intermittent asthma often responds well to an LTRA like Montair. Persistent moderate‑to‑severe disease usually needs an inhaled corticosteroid.
- Adherence preferences: If you dislike inhalers, an oral tablet (Montair, Zafirlukast) may be easier to stick with.
- Allergy profile: Montair also helps with allergic rhinitis, so patients with combined asthma‑allergy symptoms get a dual benefit.
- Cost considerations: Generic montelukast (often sold as Montair) is cheaper than most inhaled steroids and far less pricey than biologics.
- Side‑effect tolerance: Montair’s most common side effects are mild headache or stomach upset, while inhaled steroids can cause oral thrush and growth suppression in children.

Side‑effect profile comparison
Medication | Common mild side effects | Serious adverse events | Notes for specific groups |
---|---|---|---|
Montair (montelukast) | Headache, abdominal pain, cough | Rare neuropsychiatric events (mood changes, nightmares) | Monitor children for behavioral changes |
Singulair (same active ingredient) | Identical to Montair | Same rare neuropsychiatric warnings | Brand may be pricier in some regions |
Zafirlukast | nausea, dizziness | Elevated liver enzymes, rare hepatitis | Requires liver function monitoring |
Inhaled corticosteroid (ICS) | Hoarse voice, oral thrush | Systemic effects at high dose (bone loss, cataracts) | Rinse mouth after use to prevent thrush |
Antihistamine | Dry mouth, mild drowsiness | Rare cardiac QT prolongation (first‑gen) | Second‑gen (cetirizine) have minimal sedation |
Biologic (omalizumab) | Injection site redness | Anaphylaxis (≈0.1%), parasitic infections | Given monthly in a clinic, high cost |
Cost and convenience comparison
Medication | Typical monthly price (GBP) | Dosing frequency | Administration route |
---|---|---|---|
Montair (generic montelukast) | £6‑£9 | Once daily | Oral tablet or chewable |
Singulair (brand) | £12‑£15 | Once daily | Oral tablet |
Zafirlukast | £10‑£13 | Twice daily | Oral tablet |
Inhaled corticosteroid (e.g., Fluticasone propionate) | £18‑£25 | Once or twice daily | Inhaler |
Antihistamine (cetirizine) | £4‑£7 | Once daily | Oral tablet |
Biologic (omalizumab) | £350‑£420 (per injection) | Monthly | Subcutaneous injection |
Best‑fit summary - who should pick Montair?
Montair shines for patients who:
- Have mild‑to‑moderate asthma that is well‑controlled with occasional flare‑ups.
- Also suffer from seasonal allergic rhinitis and want one pill to cover both.
- Prefer a once‑daily oral dose over inhalers or injections.
- Need a low‑cost option that is widely available in the UK.
If you experience frequent nighttime symptoms, need rapid rescue relief, or have severe asthma despite a low‑dose inhaled corticosteroid, you’ll likely need to move up to an ICS or add a biologic. For those who can’t tolerate inhalers because of coordination issues, Zafirlukast may be an alternative, but watch liver tests.
Quick takeaways
- Montair is the cheapest generic LTRA, taken once daily.
- Its dual action on asthma and allergy makes it a convenient first‑line choice for many.
- Serious side effects are rare, but monitor children for mood changes.
- When asthma is moderate‑to‑severe, inhaled corticosteroids or biologics provide stronger inflammation control.
- Cost‑sensitive patients often stay with Montair unless symptoms dictate stepping up therapy.
Frequently Asked Questions
Can I take Montair and an inhaled corticosteroid together?
Yes. Many clinicians prescribe a low‑dose inhaled corticosteroid for baseline control and add Montair to help with exercise‑induced or allergen‑triggered symptoms. The combination is safe and can reduce the need for higher steroid doses.
Is Montair safe for children?
Montair is approved for children as young as 6 months for allergic rhinitis and from 12 months for asthma. The biggest concern is the rare neuropsychiatric effect, so parents should watch for mood swings, agitation, or vivid dreams.
How does Montair differ from Singulair?
There is no active‑ingredient difference; both contain montelukast. The distinction is brand vs. generic pricing and packaging. In the UK, the generic Montair is usually cheaper and available in chewable forms for kids.
Why might a doctor prescribe Zafirlukast instead of Montair?
Zafirlukast may be chosen if a patient cannot tolerate montelukast’s taste or formulation. However, its twice‑daily dosing and liver‑enzyme monitoring requirement make it less convenient for most patients.
Are there any food or drug interactions with Montair?
Montair has few interactions, but strong CYP3A4 inhibitors (e.g., ketoconazole) can raise its blood levels. Grapefruit juice, a CYP3A4 blocker, is also best avoided in large amounts.
anshu vijaywergiya
October 4, 2025 AT 18:40Hey folks, let’s take a moment to appreciate how Montair can be a real game‑changer for those juggling mild asthma and pesky seasonal allergies. Its once‑daily pill format means you’re not fumbling with inhalers during a sneeze attack, and the price point in the UK is downright friendly. Plus, the dual action on leukotrienes helps keep both your airways and nasal passages calm. Remember, consistency is key – taking it at the same time each day maximizes its preventive magic. If you’re on a budget, the generic version often slips under £10 a month, which is a sweet deal compared to inhaled corticosteroids or pricey biologics. Stay tuned for more tips, and feel free to share your own experiences with Montair!