Tag: 2x2 crossover
Crossover Trial Design: How Bioequivalence Studies Are Structured
By Lindsey Smith On 22 Nov, 2025 Comments (3)
Crossover trial designs are the gold standard for bioequivalence studies, using each participant as their own control to reduce variability and sample size. Learn how 2x2 and replicate designs work, why washout periods matter, and what regulators require.
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