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Tag: replicate crossover design

Crossover Trial Design: How Bioequivalence Studies Are Structured

By Lindsey Smith    On 22 Nov, 2025    Comments (3)

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Crossover trial designs are the gold standard for bioequivalence studies, using each participant as their own control to reduce variability and sample size. Learn how 2x2 and replicate designs work, why washout periods matter, and what regulators require.

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